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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd10f8021a619d73c500553602a6eab826d3f3b5affb52fd15cf45b7f6e744fbe' 
  AND token = 'mIHnIB/Hl/riJHbbH0ROagniUsHkDxTgx0jOpSFnNyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}