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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8cbf1fccfe6286fa011b375f44214311ec84c3065be4f2bc93c35f49d8ff6b8' 
  AND token = 'O6TPEy5FSBDYdj58Dc4JsNK6tVA9OMXxx3HBm3VJSuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}