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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3989dab647f3406eeda9d3276b5372f6539d3ec7ff1d7778852d9ec9c2e516' 
  AND token = 'Mx3bHq+cVht1T5AN3DqVskjXYfKx1xZLURhAXVlFPA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}