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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d30b748b626b10de886bd25e3d0b0134fd8382f60f15f3d7cdbcb41dc092f5' 
  AND token = '2FCmVeAqcnvs/4YKFPFcqig3GW1xR+KQkF3kCqa0yfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}