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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81bc0f8e32a70034d668a6b4b562f950ff95fad34d991d1bd602c167c95043c' 
  AND token = 'XvLZ6CCKyq9wF0CugQ4Way+qBUt3wYWNIgk+nk6d6ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}