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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77cf9f022ad722422959e54b1cc315fbfa1d8bd97b336ee594506169decc57e' 
  AND token = 'Wuv934ptZvSCOLWsMBv4gdedT2cDtIEgv0XsIZM6CDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}