SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de05e0a6d0605a432216657af583a85a4bef96a642c51390f6e26af75752d59' 
  AND token = 'AnFIMR80j5PBF0czdouwOEJtUGzboOY9gviJ9H+JU9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}