SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd223b6fdc427afa02d75e7eefec392e56349abe05af21be5e986cbd33d33b83' 
  AND token = 'QN+kmE3hKHOayN+FbIHkYsDCF8cuRJYy4LIF9q7oX3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}