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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a03d7d3da1bb202857e72118bf96c3d66a6b482b1490e18f0536c0386e491d62' 
  AND token = '5tjzM/uScpDqyQ1SauWKKNSY/Ehn3KQzEVI8+z1K0G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}