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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b294a45266e0cafce3ce16ed1bbed6f8e30bca861955e41899af776400fd5d95' 
  AND token = 'vOPjhQRnoW5Q3XhEgbRJ5J5RXx+SKqXSKEWRYtCW+6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}