SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5d89412717a9953db56c6a5d27d942c374aae6d8ba866222a80ec2616f828d' 
  AND token = 'aHQdUcrUtcrUXeR+iC9UElvqWHx332YnijzkNv3AqNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}