SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c9383508dc0b709463ac3d1778d9821f68e8d6b26d6c17cca08cf78fc3780b' 
  AND token = 'mnjFYy7Ft1c3EQDcLygW7f+IVyjlqVaPkAedOGkQf1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}