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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2955b16f6300c9d8b733302ca425f3b661ef16dced2db21450ae1ba79a01a6df' 
  AND token = 'tEaQ7AYc1lvdVC4e8r8s5c/vPaEB5gIJmVB7ZIf0VeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}