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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f28f849f958a6d6f4915e06bffc63518613fc4555640cf8ee1f556ca86b90ab4' 
  AND token = 'H6Kp4y2P1ck1JVXExggdUpum/bAY3Dkg+u+0uGIXdSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}