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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0fa6697c474b5b6d4f4ba65c5a07205227d1697e21da6480898e30fa15ce5e' 
  AND token = 'huScxID8oEq/QsmnMZIA3MB3iH5SJHmF4DBcg80wEqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}