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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6b337abfa7d0a0a9119c0b1a0af7725e37b9bc00cd4f841dcb08267f76b390' 
  AND token = 'F/y+0mDMstjFM7wPgc4X9GWWjp7Gkoi9FXTDbRMdjNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}