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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf7c4f843f49c213fa61160ae5fcf96c96c14f957551547c693b07ec4871846' 
  AND token = 'sF6swgCzj9kKdlvvG1P3kEgnFEmdpYWGwW3UYFWY5LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}