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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4e3b25ac49c35fe9a4a358d3e5dc413af8faf97887fa0dfcee183002a229ed0' 
  AND token = 'fhS1nDtQX2Vlko8s4WoTwMbPXpfoMGZTvSGUMzalP7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}