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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fddd1bf8f4dc970bbfab48631e5cc9c040a5ea0fc43bc302d7df6e80b770daf' 
  AND token = 'DEOKQ5zUp4Vxwk0cP8hTdrkY73xlgouU0Jx+bgtTmac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}