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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74cd4a6ce9504c0a1ea081dc98f0a5a5221fad4c026aecb7b232095fc559d143' 
  AND token = 'gwvDl/UnMyDca4XFZR+UuyVi9uOaK5K5wlVuBgNouro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}