SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af541f6e3a4c7bd12910145a82a3ae04c96006769931fc39451d564ae0946eaf' 
  AND token = 'SHL9SUClI1VBgFOIK+Fm3tPWUc2Ivdt9T44eKHFAjnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}