SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '064c76dd3418f1184899813e377cae4714e4186c5edf29d2bb04c3e06fecf387' 
  AND token = 'IIgoH/kMEDS3+A5JvWLTipGQ+JRtcNq8sPWeuoLHNR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}