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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd821f51eff587e52bc6d9b4febf5c5f961cbd3fa83083a22738523a474e1c9b3' 
  AND token = '01I8sRmSnpxd8T5mCN0K85F55beGOPkEZDPZg9+lm3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}