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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed418d81f72b9bc314e822d4e69eadbfe05cdf4637a9ac61a6d634c8e05d3e90' 
  AND token = 'eiWYnnGiKPOHR3f3p0E+tvphctnRUFuPOH+zNgE6pbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}