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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80113baa9e8ad80d305b88882c417790d140a6270e6228939eb6df9cee6c2da5' 
  AND token = 'Zvl7DWgUzB5zWTdieFO7mii64yEmkEcX26ZzDprQ1AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}