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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf5dc3105830c6c2f146d3d1ac129d83af4709d59706ef4cfe7c4a530993a61' 
  AND token = '1X7zcpNO83Vr4Gvsf32GDJMco1ciHG2mHy/ZXP2Wwek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}