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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61af92a13435920209df2e1cc2e9bf0105407856dd1ff2d04bc65b7c82737794' 
  AND token = 'CrVeTeYdL3O6sY29oCtVzgJA1KfR+uKks/xEqIdn9WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}