SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d0b62dcf784794be3d39a5e019d037a600826fe8e1b05fd378eb6893ce39e6' 
  AND token = 'AUXFSFf44MZ6ZOTrT3pUwdUGDoIJ4RgIENZYmb06kHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}