SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e548a25bfb53277ff8c02eefe2eeb8923e65a431bb7ffcf1d9cbfdd6964e8d22' 
  AND token = 'AE/f4CA49VIj+XZn99znA5P4OQ7ISkPDfRD+KQCJm7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}