SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56aa495877efa3b2b25fdc85094c340761587b023a05c8e753a1242830478ed5' 
  AND token = '2FOvWsWVB1KWyk3DQ8qF780YSHBKiSYHLEtbo3vm4EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}