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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c0b1dd1a67c77b185b4f4ce4d2c888c7c9c0e58668f8f097747b5db11214c93' 
  AND token = 'qQ5XrY+2cVFRGxweW0OWjUnFsjB429V+lkQgM8mLsjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}