SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abb124711ee2127c0806b6849000c2a9d9e7897ed42e1040cb1d7dcb99b05b37' 
  AND token = 'y6oD7hG6xCJXZjMhFeQ58UwdPT8iLdMnxXzUcRthz/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}