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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f3d3ac9bba6f71c793d4d872097f691ed8761b6431f9c9963bc97a01a279ba' 
  AND token = 'crYbWc2+pLvnZU9QB8nRZ3UdXTwj3xhc1bsF8fbEunU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}