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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b519c53e23e46971c05bebd2e4829bebab1a0e4bcd91aa3c849c36dbf019708' 
  AND token = '6l6xkU0TjvGPH847OhMhu9bqVVcrYhiAHp+hzfFE7kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}