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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9c5b94f4df114d3a5f4b8c4e27aa4f800979c385604ee65f50e61284acfb784' 
  AND token = 'bDZHh8IN8EAF+UMUlFLn2jHcaOBknHiPKrWhCG1+dsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}