SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e34788c68c4a12bf53def8653328eff0d28c47de9cc9dd1570d67a575be6ae30' 
  AND token = 'chZnhfi/G3wgiuFrXJp39NpHL8OD29mTNZvU4fbBw5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}