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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb0e09de91558579b4917d128052e4d1bf9ec1246914530bdb1d2d624903a49' 
  AND token = 'vEK0xJ0UNV5UCZHN8XnLdJANYeZfc8vqhylKlV1T/3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}