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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02b70aac8d0b3fcbb4d11024731219b1fd80e3615ce1a6ca6e0e015c7814003' 
  AND token = 'TNTwU+NX+KhnwIyCh8MM7ZHe51OmIPRgZeWE7g9IY0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}