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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf3eccd1166d17c66b5eec4c89d0f3bca935ba52921cd7cd9b5526161161dce' 
  AND token = 'qxoreFFaT+8SI7T9b7B5q1xPs8dOBG1dbcXTZekOwUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}