SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39beee0b7bef7eed6206e0f8ca52bc0e381ac09f3a0d8d34a1659ad37f74ff81' 
  AND token = 'FBHsFLUp472+xyfZFBcvxK4r6P7fFmWX9HBCN3ISS6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}