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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1a5a3af9d97c5fe595c5c6c329ad6f9b977221b10dd68d5cf7538eb8b63853' 
  AND token = 'i5bTitPOHH9TXvtFcPABn4VC9ZwCrbWe1uF1kOJ3vLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}