SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89af450789bd19ff76b3263eb74f9205f1fa85ad6f4f2cc8232afdd2cb6c216a' 
  AND token = 'OUFcE1F38a5yrsAEKlHYdRX8QVgtIWy7KC+AkDZsEmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}