SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bc661e277cb58f788d42e949bdae9f463d3ea928da29e9e56e25a7ea8378b7f' 
  AND token = 'ukPR8ZkI+5zNwUcB8MURB4odnsaRdHNKnTcTgo6pSu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}