SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '397b0f258cdcb804020c4dc3b0732dd05b7aa0432af64c0a83510074f1798783' 
  AND token = 'e75QpWWccQ0hPzAmRlziBYKTl1BnvwrFHUoWotvt4vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}