SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd380e8dc9852921607bde680bac444c938c2aa5e65c64610ac2b69a06d51573' 
  AND token = 'PqEQ4wbKWY8wevSRwqRBB2jZm+K5uF1wxH9iEWPlXxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}