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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014e1123725c449571f280f6578c67558f7f81f3efbb7f84168b4538a6b6003b' 
  AND token = 'qlOvdHWNIs8sj9fTe2HmWDCtrOADqHq4DGCRiXGKTGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}