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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456d7355428a1264ddf942b54250ba5ee98d1981eaeba1b9bfce99628a208943' 
  AND token = 'K6AlAmLn1O2e62fL5a0nZ9xJcMQxo+RS2q6y+P9w94I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}