SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db6192907db2fe398b07fbdd627bcb73424ea45f9e75e9d02ef3929682520da3' 
  AND token = 'zTERDQsGiOWfn6qxL+Q5f/uoOnzXbNoIFEq4MKbdH1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}