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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61b7b2ef7604c4506a83607a0b8874288ecce71efc2846210acc4a90a8449b4' 
  AND token = 'DXtUpgW2p52d0s4TS8UDe20Uvip2vADNTQP9zKWjG0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}