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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7da50513b4554ff2b3c6c38cc661c56f9482463e6218003771141cc96056a063' 
  AND token = 'xWpFV1/LDjvk63zTfEoK9b+BpFt9dgP6vZEUkZE3OxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}